Vol. 4, Issue 2, Part A (2022)

Nonalcoholic fatty liver disease influences 25% of the people and can keep going to cirrhosis with insufficient treatment options. Therefore, early diagnosis of nonalcoholic fatty liver disease is very important. The study aims to measure the serum concentrations of Afamin (AFM) in non-alcoholic fatty liver cases (NAFLD) and to determine their link with the stage of the disease. The study comprised (60) cases suffering from non-alcoholic fatty liver disease in Kirkuk governorate, their ages varied between (30-75), The control group comprised (30) healthy individuals who did not suffer from non-alcoholic fatty liver disease (NAFLD).The concentration of Afamin in the blood was measured, as well as some biochemical indicators were calculated such as (Alanine aminotransferase ALT, Aspartate aminotransferase AST, Alkaline transferase ALP, Gamma-glutamyl transferase GGT). The concentration of Afamin was seen to be significantly higher in cases with non-alcoholic fatty liver disease at a probability level (p≤ 0.001) as compared to the control group. Through these results, it was concluded that the Afamin hormone can be handled as an index of non-alcoholic fatty liver disease (NAFLD).