Vol. 6, Issue 1, Part B (2024)

Acinetobacter baumannii is one of the most critical drug-resistant pathogens globally. WHO has highlighted that drug-resistant microorganisms significantly threaten the most vulnerable hospital patients, emphasizing the urgent need for new antibiotic research and development.

A. baumannii can survive on dry surfaces for up to a month and employs various drug resistance mechanisms, including efflux pumps, drug-inactivating enzymes, and mutations targeting drugs. Infections caused by these bacteria can lead to severe illnesses such as septicemia, pneumonia, and urinary tract infections. The WHO has classified A. baumannii as a critical priority pathogen, underlining the necessity for new antibiotics. This study aimed to identify antibiotics in plant extracts and assess their efficacy. A. baumannii was isolated and identified from patients in several hospitals in Basra Governorate using traditional and molecular methods. The study tested the effectiveness of aqueous and alcoholic pomegranate peel extracts against these multi-antibiotic- resistant bacteria, and the results demonstrated the extracts' efficacy.