Vol. 7, Issue 2, Part A (2025)

This study offers an in-depth examination of the notable advancements in medicinal chemistry, emphasizing the Synthesis and mechanisms of many classes of bioactive chemicals. The discourse underscores the progression of antibiotic drugs, specifically focusing on sulfonamides, β-lactams, and azo compounds. The article elucidates the mechanisms of action, therapeutic applications, and obstacles related to these drugs while also confronting developing issues such as antimicrobial resistance and the necessity for innovative therapeutic tactics. Sulfonamides and β-lactams continue to be essential in the management of bacterial infections, notwithstanding rising resistance, with their intricate modes of action elucidated. Azo compounds are investigated for their diverse applications, including antibacterial and anticancer characteristics. The analysis underscores the necessity of ongoing innovation in medication research to address resistant infections and enhance therapeutic results. This study discusses the significance of these discoveries for future research and clinical applications, rendering it a significant resource for academics and practitioners in medicinal chemistry.